Universiteit van Amsterdam
The University of Amsterdam is one of the largest university in The Netherlands and has a long tradition in frontline research in the Sciences. The Swammerdam Institute for Life Science in one of the three main research institutes of its Science Faculty.
Within this institute the “Molecular Microbial Physiology Research Group” characterizes molecular mechanisms of regulation of key metabolic pathways in both chemotrophic- and phototrophic bacteria. It has a leading role in microbial physiology in The Netherlands, is equipped with state-of-the-art reactor and analysis systems (e.g. HPLC) for microbial physiology, and has an extensive international network on the elucidation of signaling mechanisms and metabolic regulation in these bacteria.
Light-activated signal transduction pathways are key in this research, because they allow unprecedented temporal and spatial resolution of the process. Research in this group focuses on the molecular basis of signal transduction and on the physiological pathways under their control. More recently its interest has shifted to pathways engineered through “synthetic biology”.
A variety of pathways have been designed and expressed in cyanobacteria, thereby creating “photo-fermentative” chimerae that allow direct biofuel product formation from intermediates of the Calvin-Benson cycle. The group particularly has a long tradition in genetic research of bacteria based on gene transfer via natural transformation.
Role within the Project
Coordination of WP3 (Optimization of bioethanol producing strain), contributions in other WPs
Prof. Dr. K.J. Hellingwerf and Dr. D. Montesarchio
Postal address: Postbus 94232, 1090 GE Amsterdam, The Netherlands
Visiting address: Science Park 904, 1098 XH Amsterdam, The Netherlands